| Primary Identifier | MGI:1916863 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 80294 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables peptide-O-fucosyltransferase activity. Involved in protein O-linked glycosylation via fucose. Acts upstream of or within mesoderm formation; regulation of epithelial to mesenchymal transition; and regulation of gene expression. Is active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and sensory organ. Orthologous to human POFUT2 (protein O-fucosyltransferase 2). PHENOTYPE: Homozygous mutation of this gene results in lethality before weaning. [provided by MGI curators] |