| Primary Identifier | MGI:1919725 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 72475 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription coactivator activity. Involved in several processes, including head morphogenesis; nervous system development; and positive regulation of anterior head development. Acts upstream of or within hematopoietic progenitor cell differentiation. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; islets of Langerhans; limb; and retina. Orthologous to human SSBP3 (single stranded DNA binding protein 3). PHENOTYPE: Embryos homozygous for a gene trap mutation that deletes the proline-rich domain show a severe anterior truncation and a lethal headless phenotype (loss of fore- and midbrain). Embryos homozygous for a gene trap mutation which retains most of the proline-rich domain show normal head development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
