| Primary Identifier | MGI:1914555 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 67305 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable catalase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; integumental system; nose; and skeleton. Human ortholog(s) of this gene implicated in Barrett's adenocarcinoma and Barrett's esophagus. Orthologous to human GPX7 (glutathione peroxidase 7). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased cellular sensitivity to oxidative stress, premature death, systemic disease and increased tumor incidence. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
