| Primary Identifier | MGI:1328337 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 18392 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA replication origin binding activity and chromatin binding activity. Predicted to be involved in DNA replication initiation; positive regulation of smooth muscle cell proliferation; and regulation of cell cycle process. Predicted to act upstream of or within DNA replication. Predicted to be located in nucleoplasm. Predicted to be part of nuclear origin of replication recognition complex. Predicted to colocalize with chromosome, telomeric region. Is expressed in liver and submandibular gland. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 1. Orthologous to human ORC1 (origin recognition complex subunit 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete peri-implantation lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
