| Primary Identifier | MGI:2148793 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 114229 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables G protein-coupled peptide receptor activity and molecular adaptor activity. Involved in negative regulation of bone resorption; regulation of membrane depolarization; and regulation of monoatomic cation transmembrane transport. Acts upstream of or within signal transduction. Located in cell surface. Is expressed in alimentary system; brain; genitourinary system; sensory organ; and thymus. Used to study hypogonadotropic hypogonadism 8 with or without anosmia. Human ortholog(s) of this gene implicated in central precocious puberty 1; hypogonadism; and hypogonadotropic hypogonadism 8 with or without anosmia. Orthologous to human KISS1R (KISS1 receptor). PHENOTYPE: Homozygous null mutations result in male and female infertility associated with abnormal sexual maturation and hypogonadotropic hypogonadism. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
