Primary Identifier | MGI:3651956 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 102635290 |
Mgi Type | antisense lncRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity; ribonucleoprotein complex binding activity; and transcription cis-regulatory region binding activity. Acts upstream of or within with a negative effect on inflammatory response and transcription by RNA polymerase II. Acts upstream of or within gene expression; nucleosome organization; and response to lipopolysaccharide. PHENOTYPE: Homozygous null mice exhibit increased susceptibility to LPS-induced endotoxin shock and to induced acute pancreatitis. [provided by MGI curators] |