Primary Identifier | MGI:2653629 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 242620 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and sequence-specific DNA binding activity. Acts upstream of or within several processes, including nervous system development; positive regulation of neuroblast proliferation; and stem cell fate specification. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human DMRTA2 (DMRT like family A2). PHENOTYPE: Mice homozygous for a targeted allele exhibit telencephalon hypoplasia, reduced cerebral cortex area, absent hippocampus, small olfactory bulb, disorganized medial cortex and decreased cortical neurons due to reduced proliferation of neuronal precursors. [provided by MGI curators] |