| Primary Identifier | MGI:107477 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 20460 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Acts upstream of or within several processes, including chordate embryonic development; embryonic organ development; and non-motile cilium assembly. Predicted to be located in cytoplasm; microtubule organizing center; and nucleoplasm. Predicted to be part of procentriole replication complex. Predicted to be active in microtubule organizing center. Is expressed in several structures, including alimentary system; brain; integumental system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 7. Orthologous to human STIL (STIL centriolar assembly protein). PHENOTYPE: Mice homozygous for disruptions in this gene die as embryos with various neural tube defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
