Primary Identifier | MGI:894316 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 17346 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP binding activity and protein serine/threonine kinase activity. Involved in intracellular signal transduction; protein phosphorylation; and response to salt stress. Acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; integumental system; liver; nervous system; and nose. Orthologous to human MKNK1 (MAPK interacting serine/threonine kinase 1). PHENOTYPE: Homozygous null mice are viable and fertile with no gross abnormalities. [provided by MGI curators] |