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Protein Coding Gene : Toe1 target of EGR1, member 1 (nuclear)
Primary Identifier  MGI:1915526 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  68276
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable poly(A)-specific ribonuclease activity and snRNA binding activity. Predicted to be involved in snRNA 3'-end processing. Predicted to be located in cytoplasm and nuclear body. Predicted to be active in Cajal body. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and hemolymphoid system. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 7. Orthologous to human TOE1 (target of EGR1, exonuclease).
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality before E11.5. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI413517,
  • target of EGR1, member 1 (nuclear),
  • 4933424D16Rik,
  • 4930584N22Rik,
  • MGI:1918394,
  • RIKEN cDNA 4933424D16 gene,
  • Toe1,
  • AI413517,
  • MGI:2140253,
  • RIKEN cDNA 4930584N22 gene
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