| Primary Identifier | MGI:1917853 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 70603 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA N-glycosylase activity; DNA binding activity; and MutSalpha complex binding activity. Involved in negative regulation of necroptotic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in familial adenomatous polyposis; familial adenomatous polyposis 2; stomach cancer; and stomach carcinoma. Orthologous to human MUTYH (mutY DNA glycosylase). PHENOTYPE: Homozygous mutant mice are viable and show no increase in tumor incidence relative to wild-type through 17 months of age. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
