Primary Identifier | MGI:95760 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 14664 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glycine:sodium symporter activity. Involved in several processes, including glycine import across plasma membrane; positive regulation of biosynthetic process; and regulation of glycinergic synaptic transmission. Acts upstream of or within glycine secretion, neurotransmission. Located in plasma membrane. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and liver and biliary system. Used to study glycine encephalopathy. Orthologous to human SLC6A9 (solute carrier family 6 member 9). PHENOTYPE: Homozygous null mice die shortly after birth exhibiting breathing and movement deficiencies. [provided by MGI curators] |