Primary Identifier | MGI:1858493 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 53418 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable galactosyltransferase activity. Acts upstream of or within cerebellar Purkinje cell layer development; learning or memory; and locomotory behavior. Predicted to be located in nucleoplasm. Predicted to be active in Golgi apparatus. Is expressed in early conceptus; eye; gonad; and nervous system. Orthologous to human B4GALT2 (beta-1,4-galactosyltransferase 2). PHENOTYPE: Mice homozygous for a null allele exhibit decreased brain weight, ectopic Purkinje cells in the cerebellum, and impaired spatial learning and coordination. [provided by MGI curators] |