Primary Identifier | MGI:1916322 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 69072 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in rRNA processing and ribosomal large subunit biogenesis. Predicted to be located in chromosome. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nuclear periphery and nucleolus. Orthologous to human EBNA1BP2 (EBNA1 binding protein 2). PHENOTYPE: Mice homozygous for a knock-out allele show partial morula compaction and complete embryonic lethality. In vitro outgrowth assays show that embryos fail to hatch from the zona pellucida and die after 3 days in culture. [provided by MGI curators] |