Primary Identifier | MGI:1924705 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 109263 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Acts upstream of or within negative regulation of heterochromatin formation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; liver; male reproductive system; spleen; and urinary system. Orthologous to human RLF (RLF zinc finger). PHENOTYPE: Mice homozygous for a hypomorphic ENU-induced allele exhibit postnatal lethality. Only a few mice survive to weaning age exhibiting a decreased body size. [provided by MGI curators] |