| Primary Identifier | MGI:1914216 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 66966 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables tRNA dimethylallyltransferase activity. Involved in tRNA modification. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 35. Orthologous to human TRIT1 (tRNA isopentenyltransferase 1). PHENOTYPE: Mice homozygous for a knock-out allele show normal blastocyst formation but exhibit embryonic lethality prior to organogenesis with no morphological primitive node or head folds present. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
