| Primary Identifier | MGI:103257 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 16330 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables inositol-1,4,5-trisphosphate 5-phosphatase activity and phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity. Involved in phosphatidylinositol dephosphorylation. Acts upstream of or within several processes, including flagellated sperm motility; in utero embryonic development; and regulation of protein processing. Located in cytosol and membrane. Is expressed in several structures, including alimentary system; genitourinary system; liver; lung; and spleen. Orthologous to human INPP5B (inositol polyphosphate-5-phosphatase B). PHENOTYPE: Homozygous null male mice are infertile with a disruption in spermatogenesis and a defect in adherens junctions processing. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
