Primary Identifier | MGI:2156003 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 76793 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription regulator inhibitor activity. Involved in negative regulation of canonical NF-kappaB signal transduction. Is active in nucleus. Is expressed in several structures, including branchial arch; cerebral cortex; gut epithelium; metanephros; and sensory organ. Orthologous to human SNIP1 (Smad nuclear interacting protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit prenatal lethality. [provided by MGI curators] |