Primary Identifier | MGI:1346335 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 24084 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in flagellated sperm motility. Acts upstream of or within inner dynein arm assembly. Located in microtubule organizing center. Is active in axonemal A tubule inner sheath and sperm flagellum. Is expressed in foregut-midgut junction and inner ear. Orthologous to human TEKT2 (tektin 2). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit male infertility and impaired motility of both sperm flagella and tracheal cilia due to altered dynein inner arm morphology and function. [provided by MGI curators] |