Primary Identifier | MGI:2679630 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 332937 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including brain; early conceptus; neural ectoderm; ovary; and vomeronasal organ. Orthologous to human TFAP2E (transcription factor AP-2 epsilon). PHENOTYPE: Mice homozygous for a knock-in allele exhibit impaired olfactory bulb neuronal layer development. [provided by MGI curators] |