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Protein Coding Gene : Gjb5 gap junction protein, beta 5
Primary Identifier  MGI:95723 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  14622
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable gap junction channel activity. Acts upstream of or within labyrinthine layer morphogenesis; spongiotrophoblast differentiation; and trophoblast giant cell differentiation. Predicted to be part of connexin complex. Is expressed in several structures, including early conceptus; reproductive system; sensory organ; and skin. Orthologous to human GJB5 (gap junction protein beta 5).
PHENOTYPE: Mice homozygous for a null allele exhibit some embryonic lethality, reduced weight and reduced placental development. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-10100,
  • Gjb-5,
  • MGD-MRK-10095,
  • Cx31.1,
  • connexin 31.1,
  • Cnx31.1,
  • Gjb5,
  • gap junction protein, beta 5
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Features --> Cross References

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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