Primary Identifier | MGI:3045221 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 384059 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable signaling receptor activity. Acts upstream of or within defense response to protozoan. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human TLR12P (toll like receptor 12, pseudogene). PHENOTYPE: Mice homozygous for a null mutation exhibit a greatly increased susceptibility to kidney infection by uropathogenic bacteria. [provided by MGI curators] |