Primary Identifier | MGI:1914775 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 67525 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; transcription coactivator activity; and ubiquitin protein ligase activity. Involved in positive regulation of antifungal innate immune response. Acts upstream of or within negative regulation of epithelial to mesenchymal transition. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; maxillary process; sensory organ; and submandibular gland primordium. Orthologous to human TRIM62 (tripartite motif containing 62). PHENOTYPE: Mice heterozygous or homozygous for a targeted allele exhibit increased tumorigenesis. [provided by MGI curators] |