| Primary Identifier | MGI:97252 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 17877 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within several processes, including skeletal muscle cell differentiation; skeletal system morphogenesis; and somitogenesis. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and musculature. Orthologous to human MYF5 (myogenic factor 5). PHENOTYPE: Homozygotes for targeted null mutations exhibit delayed appearance of myotomal cells in somites, and lack the distal portion of ribs resulting in inability to breathe and lethality at birth. Other mutants lack the rib phenotype. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
