Primary Identifier | MGI:3652045 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 622480 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-macromolecule adaptor activity. Involved in spermatogenesis; transposable element silencing by piRNA-mediated DNA methylation; and transposable element silencing by piRNA-mediated heterochromatin formation. Located in nucleus. Is expressed in germ cell of testis. Orthologous to human SPOCD1 (SPOC domain containing 1). PHENOTYPE: Homozygous knockout affects DNA methylation of transposable elements, leading to male sterility. [provided by MGI curators] |