Primary Identifier | MGI:1349163 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 20970 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Predicted to be involved in cell adhesion; cell migration; and regulation of cell migration. Located in microspike. Is expressed in several structures, including brain; limb; lower jaw; urinary system; and vibrissa follicle. Human ortholog(s) of this gene implicated in obesity. Orthologous to human SDC3 (syndecan 3). PHENOTYPE: Homozygotes for a targeted null mutation exhibit reduced susceptibility to diet-induced obesity to a greater extent in male versus female mice. Mice heterozygous for a null allele exhibit decreased susceptibility to diet-induced obesity. [provided by MGI curators] |