| Primary Identifier | MGI:108046 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 16792 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables enzyme binding activity and protein sequestering activity. Involved in several processes, including lysosomal transport; regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in lysosome. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Orthologous to human LAPTM5 (lysosomal protein transmembrane 5). PHENOTYPE: Mice homozygous for a null allele exhibit increased T cell proliferation, increased IL-2 production and a prolognged type IV hypersensitivity response. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
