| Primary Identifier | MGI:2444233 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 213541 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables N6-methyladenosine-containing RNA reader activity. Involved in several processes, including hematopoietic stem cell proliferation; negative regulation of gene expression; and spermatogonial cell division. Located in cytoplasm and nucleus. Is expressed in brain; intestine; and liver. Orthologous to human YTHDF2 (YTH N6-methyladenosine RNA binding protein F2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit female infertility and background-sensitive preweaning lethality. Male homozygotes generated by different targeting strategies show differing reproductive phenotypes ranging from normal male fertility to hypofertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
