Primary Identifier | MGI:1915848 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 68598 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable Hsp70 protein binding activity. Predicted to be located in cytosol; intercellular bridge; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system and retina. Orthologous to human DNAJC8 (DnaJ heat shock protein family (Hsp40) member C8). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal visceral yolk sac morphology, defects in placentation with abnormal trophoblast layer formation, and complete lethality throughout fetal growth and development. [provided by MGI curators] |