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Protein Coding Gene : Dnajc8 DnaJ heat shock protein family (Hsp40) member C8

Primary Identifier  MGI:1915848 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  68598
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable Hsp70 protein binding activity. Predicted to be located in cytosol; intercellular bridge; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system and retina. Orthologous to human DNAJC8 (DnaJ heat shock protein family (Hsp40) member C8).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal visceral yolk sac morphology, defects in placentation with abnormal trophoblast layer formation, and complete lethality throughout fetal growth and development. [provided by MGI curators]
  • synonyms:
  • Dnajc8,
  • AU044514,
  • RIKEN cDNA 1110021D09 gene,
  • expressed sequence AL024084,
  • MGI:2140412,
  • expressed sequence AU019262,
  • expressed sequence AU044514,
  • MGI:2140493,
  • MGI:2140449,
  • RIKEN cDNA 2010009J04 gene,
  • AL024084,
  • MGI:1923773,
  • AU019262,
  • DnaJ heat shock protein family (Hsp40) member C8,
  • 2010009J04Rik,
  • 1110021D09Rik

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4 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Mouse features --> Functions (GO terms)

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