Primary Identifier | MGI:109339 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 14050 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity; protein tyrosine phosphatase activity; and protein tyrosine/serine/threonine phosphatase activity. Acts upstream of or within protein dephosphorylation. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including branchial arch; genitourinary system; limb bud; rhombomere; and sensory organ. Orthologous to human EYA3 (EYA transcriptional coactivator and phosphatase 3). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit abnormal heart function, decreased grip strength and increased exploratory behavior. [provided by MGI curators] |