Primary Identifier | MGI:2446213 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 230787 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in regulation of B cell activation. Acts upstream of or within T cell receptor signaling pathway. Located in cytoplasm and nucleus. Orthologous to human THEMIS2 (thymocyte selection associated family member 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal B cell development, activation, and antibody responses. [provided by MGI curators] |