Primary Identifier | MGI:3650254 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 100503878 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables promoter-specific chromatin binding activity. Involved in regulation of gene expression and regulation of lymphocyte differentiation. Acts upstream of or within NK T cell differentiation and natural killer cell differentiation. Predicted to be located in nucleus. Orthologous to human ZNF683 (zinc finger protein 683). PHENOTYPE: Mice homozygous for a gene trap allele exhibit reduced mature NKT cells and altered susceptibility to MCMV infection. [provided by MGI curators] |