Primary Identifier | MGI:3043288 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 329954 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables voltage-gated calcium channel activity. Acts upstream of or within several processes, including flagellated sperm motility; sodium ion transport; and sperm capacitation. Located in acrosomal vesicle and sperm principal piece. Part of CatSper complex. Orthologous to human CATSPER4 (cation channel sperm associated 4). PHENOTYPE: Mice homozygous for this mutation are viable and exhibit no gross physical or behavioral abnormality. Although wild-type and homozygous mutant females bred to wild-type males exhibit similar fertility, male homozygotes are infertile. [provided by MGI curators] |