Primary Identifier | MGI:106637 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 230810 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and zinc:proton antiporter activity. Involved in zinc ion import into mitochondrion. Located in mitochondrial inner membrane and zymogen granule membrane. Is expressed in adrenal gland; embryo; and lung. Orthologous to human SLC30A2 (solute carrier family 30 member 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal mammary gland development during lactation, abnormal zinc levels in the mammary gland and milk, impaired lactation and decreased litter survival. [provided by MGI curators] |