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Protein Coding Gene : Stmn1 stathmin 1

Primary Identifier  MGI:96739 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  16765
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable tubulin binding activity. Acts upstream of or within several processes, including axonogenesis; mitotic cytokinesis; and negative regulation of microtubule polymerization. Located in cytosol and membrane. Is expressed in early conceptus; genitourinary system; lung; nervous system; and sensory organ. Orthologous to human STMN1 (stathmin 1).
PHENOTYPE: Mice homozygous for a targeted null mutation appear normal as young animals, but develop a late-onset appearance of axonal lesions in the central and peripheral nervous systems. [provided by MGI curators]
  • synonyms:
  • p18,
  • Lap18,
  • oncoprotein18,
  • 19K,
  • expressed sequence AI131641,
  • PR22,
  • PP17,
  • MGI:2146799,
  • Stmn1,
  • SMN,
  • Lag,
  • PP18,
  • op18,
  • prosolin,
  • leukemia-associated gene,
  • p19,
  • leukemia associated phosphoprotein p18,
  • pig,
  • stathmin 1,
  • AI131641,
  • MGD-MRK-11729,
  • metablastin

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For