Primary Identifier | MGI:96739 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 16765 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable tubulin binding activity. Acts upstream of or within several processes, including axonogenesis; mitotic cytokinesis; and negative regulation of microtubule polymerization. Located in cytosol and membrane. Is expressed in early conceptus; genitourinary system; lung; nervous system; and sensory organ. Orthologous to human STMN1 (stathmin 1). PHENOTYPE: Mice homozygous for a targeted null mutation appear normal as young animals, but develop a late-onset appearance of axonal lesions in the central and peripheral nervous systems. [provided by MGI curators] |