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Protein Coding Gene : Syf2 SYF2 homolog, RNA splicing factor (S. cerevisiae)
Primary Identifier  MGI:1915842 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  68592
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within several processes, including gastrulation; in utero embryonic development; and mitotic G2 DNA damage checkpoint signaling. Located in nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; and embryo. Orthologous to human SYF2 (SYF2 pre-mRNA splicing factor).
PHENOTYPE: Mice homozygous for a gene trapped allele fail to undergo normal gastrulation and exhibit complete embryonic lethality, severely impaired embryonic development, and abnormal cell cycle checkpoint function. [provided by MGI curators]
  • synonyms:
  • GCIP-interacting protein p29,
  • Ntc31,
  • SYF2 homolog, RNA splicing factor (S. cerevisiae),
  • p29,
  • 1110018L13Rik,
  • MGI:107332,
  • CCNDBP1 interactor,
  • DNA segment, Chr 4, Brigham & Women's Genetics 1551 expressed,
  • MGD-MRK-35798,
  • Syf2,
  • mp29,
  • D4Bwg1551e,
  • Cbpin,
  • Gcipip,
  • RIKEN cDNA 1110018L13 gene
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3 Involved In Mutations

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4 Pathways

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