Primary Identifier | MGI:1333805 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 14105 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity. Involved in RNA splicing, via transesterification reactions; cytosolic transport; and negative regulation of mRNA splicing, via spliceosome. Located in nucleoplasm. Is expressed in several structures, including branchial arch; central nervous system; foregut-midgut junction; sensory organ; and testis. Orthologous to human SRSF10 (serine and arginine rich splicing factor 10). PHENOTYPE: Mice homozygous for a null allele exhibit fetal and neonatal lethality associated with edema and cardiac defects. [provided by MGI curators] |