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Protein Coding Gene : Pnrc2 proline-rich nuclear receptor coactivator 2
Primary Identifier  MGI:106512 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  52830
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in P-body and nucleus. Is expressed in several structures, including brain ventricular layer; genitourinary system; retina; and thymus primordium. Orthologous to human PNRC2 (proline rich nuclear receptor coactivator 2).
PHENOTYPE: Mice homozygous for a null allele exhibit decreased body weight, decreased percent body fat, resistance to diet-induced obesity, increased energy expenditure and increase heat production. [provided by MGI curators]
  • synonyms:
  • 0610011E17Rik,
  • proline-rich nuclear receptor coactivator 2,
  • MGD-MRK-34206,
  • RIKEN cDNA 0610011E17 gene,
  • Pnrc2,
  • MGI:1915049,
  • DNA segment, Chr 4, Brigham & Women's Genetics 0593 expressed,
  • D4Bwg0593e
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Features --> Cross References

Genome

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3 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

3 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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