Primary Identifier | MGI:2682254 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 230848 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in DNA damage response and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system. Orthologous to human ZBTB40 (zinc finger and BTB domain containing 40). PHENOTYPE: Male mice homozygous for a knock-out allele show a reduction in lumbar spine areal bone mineral density and decreased vertebral bone mass with reductions in trabecular bone volume, trabecular number and connectivity density. [provided by MGI curators] |