| Primary Identifier | MGI:1923935 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 230861 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables translation initiation factor activity. Involved in positive regulation of translation and spermatid development. Acts upstream of or within positive regulation of meiosis I; positive regulation of protein phosphorylation; and spermatogenesis. Is active in intracellular membraneless organelle and synapse. Is expressed in nervous system; neural retina; and submandibular gland primordium. Orthologous to human EIF4G3 (eukaryotic translation initiation factor 4 gamma 3). PHENOTYPE: Mice homozygous for an ENU induced allele exhibit decreased testes weight, azoospermia, and arrested male meiosis. Mice homozygous for a gene trapped allele exhibit small testes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
