Primary Identifier | MGI:1098229 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 16559 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule motor activity. Involved in anterograde dendritic transport of neurotransmitter receptor complex. Acts upstream of or within microtubule-based process; protein-containing complex localization; and vesicle-mediated transport. Located in several cellular components, including cytoskeleton; periciliary membrane compartment; and photoreceptor cell cilium. Part of kinesin complex. Is active in postsynapse. Is expressed in central nervous system; retina; and testis. Orthologous to human KIF17 (kinesin family member 17). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired anterograde neuron transport, reduced NMDA-mediated synaptic currents, impaired synaptic plasticity, impaired long term object recognition memory, impaired spatial learning, and impaired contextual conditioning. [provided by MGI curators] |