Primary Identifier | MGI:1920412 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 73162 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in cellular response to nutrient levels; protein deubiquitination; and protein stabilization. Predicted to act upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; protein K27-linked deubiquitination; and protein K48-linked deubiquitination. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in axial skeleton; olfactory epithelium; pancreas; and vomeronasal organ. Orthologous to human OTUD3 (OTU deubiquitinase 3). PHENOTYPE: Homozygous knockout results in decreased susceptibility to RNA virus infection. [provided by MGI curators] |