Primary Identifier | MGI:1196627 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 15565 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables G protein-coupled serotonin receptor activity. Involved in cerebral cortex cell migration and positive regulation of TOR signaling. Located in cilium. Is expressed in aorta-gonad-mesonephros; cerebral cortex intermediate zone; cerebral cortex subventricular zone; cortical plate; and embryo. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human HTR6 (5-hydroxytryptamine receptor 6). PHENOTYPE: Male mice homozygous for some disruptions in this gene display decreased body size. Mice homozygous for a different null allele display decreased sensitivity to alcohol induced behavioral responses. [provided by MGI curators] |