| Primary Identifier | MGI:104652 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 12345 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity. Acts upstream of or within actin polymerization or depolymerization and lamellipodium assembly. Located in several cellular components, including brush border; lamellipodium; and sperm head-tail coupling apparatus. Is active in Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic density. Is expressed in brain; foregut; heart; and skeletal muscle. Orthologous to human CAPZB (capping actin protein of muscle Z-line subunit beta). PHENOTYPE: Mice homozygous for a conditional allele activated in the ear exhibit increased ABR threshold, absent DPOE, reduced vestibular function, head shaking and abnormal stereocilia length and width in the cochlea and utricle. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
