|  Help  |  About  |  Contact Us

Protein Coding Gene : Padi6 peptidyl arginine deiminase, type VI

Primary Identifier  MGI:2655198 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  242726
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable identical protein binding activity and protein-arginine deiminase activity. Involved in embryonic cleavage. Acts upstream of or within several processes, including cytoplasm organization; in utero embryonic development; and regulation of translation by machinery localization. Located in cortical granule and intermediate filament cytoskeleton. Is expressed in early embryo; ileum; and reproductive system. Orthologous to human PADI6 (peptidyl arginine deiminase 6).
PHENOTYPE: Mice homozygous for a null allele exhibit altered oocyte cytoplasmic structures that lead to a failure of zygotes to progress beyond the 2 cell stage and female infertility. [provided by MGI curators]
  • synonyms:
  • peptidyl arginine deiminase, egg and embryo abundant,
  • Padi5,
  • Padi6,
  • Pad6,
  • ePAD,
  • peptidyl arginine deiminase, type VI

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For