| Primary Identifier | MGI:1338892 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 18600 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable histone H3R26 arginine deiminase activity; nuclear estrogen receptor binding activity; and protein homodimerization activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in euchromatin. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including Harderian gland; brain; early embryo; major salivary gland; and reproductive system. Orthologous to human PADI2 (peptidyl arginine deiminase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired ATP- or calcium ionophore ionomycin-induced citrullination of mast cells or of proteins following induction of EAE. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
