| Primary Identifier | MGI:99559 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 17150 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables fibrinogen binding activity and fibronectin binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within platelet formation. Located in microfibril. Is expressed in several structures, including brain; embryo mesenchyme; eye; genitourinary system; and lung. Orthologous to human MFAP2 (microfibril associated protein 2). PHENOTYPE: Homozygotes for a knock-out allele show thrombocytopenia, delayed thrombotic occlusion following vessel injury, and prolonged bleeding from a tail vein incision. Homozygotes for a different knock-out allele exhibit marrow adipose tissue expansion, insulin resistance, and altered basal hematopoiesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
