| Primary Identifier | MGI:1921452 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 74202 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable filamin binding activity. Predicted to be involved in cell-cell adhesion and regulation of integrin activation. Predicted to be located in several cellular components, including cell junction; cell periphery; and fibrillar center. Predicted to be active in focal adhesion and stress fiber. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; heart; and hemolymphoid system gland. Orthologous to human FBLIM1 (filamin binding LIM protein 1). PHENOTYPE: Mice homozygous for one knock-out allele exhibit severe osteopenia with decreased osteoblasts and increased osteoclasts. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
