Primary Identifier | MGI:1354743 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 50762 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables carbohydrate binding activity. Contributes to ubiquitin protein ligase activity. Involved in ERAD pathway and SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within glycoprotein catabolic process. Located in endoplasmic reticulum quality control compartment. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; liver; and lung. Orthologous to human FBXO6 (F-box protein 6). PHENOTYPE: Mice homozygous for a null allele exhibit normal development and breeding. [provided by MGI curators] |