Primary Identifier | MGI:109538 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 12854 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor binding activity and neuropeptide hormone activity. Predicted to be involved in G protein-coupled receptor signaling pathway; regulation of cell migration; and regulation of circadian sleep/wake cycle, sleep. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in central nervous system and retina. Orthologous to human CORT (cortistatin). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased circulating growth hormone and adrenocorticotropin, decreased serum prolactin, and insulin resistance and increased serum glucose level in male mice. [provided by MGI curators] |